钾离子刺激下，从大鼠小脑解离的富含神经元和神经胶质细胞的培养物中[3H]γ-氨基丁酸（GABA）的钙依赖性释放。

Potassium-stimulated, calcium-dependent release of [3H]GABA from neuron- and glia-enriched cultures of cells dissociated from rat cerebellum.

作者信息

Pearce B R, Currie D N, Beale R, Dutton G R

出版信息

Brain Res. 1981 Feb 16;206(2):485-9. doi: 10.1016/0006-8993(81)90552-7.

Abstract

The release of [3H]GABA from cultures of cells dissociated from the rat cerebellum was investigated. The culture system contained a population of neurons (stellate and basket cells) which were capable of accumulating [3H]GABA and releasing it in a calcium-dependent manner in response to 50 mM potassium. In addition, the release of [3H]GABA for cultured astrocytes was found to be insensitive to potassium depolarization.

摘要

对从大鼠小脑中分离出的细胞培养物中[3H]GABA的释放进行了研究。培养系统包含一群神经元（星状细胞和篮状细胞），它们能够积累[3H]GABA，并在50 mM钾的作用下以钙依赖的方式释放它。此外，发现培养的星形胶质细胞释放[3H]GABA对钾去极化不敏感。