Koos L, Field R E
Int Surg. 1980 Jul-Aug;65(4):359-62.
A 52-year-old female had radical surgery on both breasts in 1971 and 1973 for infiltrating lobular carcinoma of the breast. One year later, multiple metastases simulating Crohn's disease were found radiologically and intraoperatively in the colon and small bowel. The pathological examination revealed multiple areas of linitis plastica type carcinoma in the colon and small bowel. Review of the breast slides showed that the original breast carcinoma was morphologically identical to the metastatic lesions. The literature is reviewed and arguments are presented to attest that signet-ring-cell carcinoma of the breast is a distinct entity, which not too infrequently metastasizes to the gastrointestinal tract.
一名52岁女性于1971年和1973年因乳腺浸润性小叶癌接受了双侧乳房根治性手术。一年后，在结肠和小肠中通过影像学和术中检查发现了多处类似克罗恩病的转移灶。病理检查显示结肠和小肠有多处皮革胃样癌灶。复查乳腺切片发现，原发乳腺癌在形态学上与转移灶相同。本文回顾了相关文献并提出论据，以证明乳腺印戒细胞癌是一种独特的实体，它常转移至胃肠道。
