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1974年落基山国家公园科罗拉多蜱传热的生态学。II. 小型哺乳动物中的感染情况

The ecology of Colorado tick fever in Rocky Mountain National Park in 1974. II. Infection in small mammals.

作者信息

Bowen G S, McLean R G, Shriner R B, Francy D B, Pokorny K S, Trimble J M, Bolin R A, Barnes A M, Calisher C H, Muth D J

出版信息

Am J Trop Med Hyg. 1981 Mar;30(2):490-6. doi: 10.4269/ajtmh.1981.30.490.

DOI:10.4269/ajtmh.1981.30.490
PMID:6263122
Abstract

Field studies of Colorado tick fever (CTF) in small mammals in Rocky Mountain National Park (RMNP) in 1974 established that Eutamias minimus and Spermophilus lateralis were the most important hosts for CTF virus and were the source of virus for immature stages of the tick vector, Dermacentor andersoni. Other species (Peromyscus maniculatus, Spermophilus richardsonii, Eutamias umbrinus) are secondary hosts. The intensity of viral activity in rodents varied greatly from locality to locality. Highest rodent infection rates were found to occur in the Moraine Park area of RMNP. Lowest infection rates occurred above 3,290 meters in altitude at Rainbow Curve and on the tundra. The prevalence of infection in rodents was constant from April--July (5--6% of animals captured were viremic) and then declined to 1.7--2.5% in August and September coincident with a decline in nymphal tick ectoparasitism. Many animals were captured which were simultaneously viremic and antibody-positive. Under field conditions, neutralizing antibody seroconversion does not always occur.

摘要

1974年在落基山国家公园(RMNP)对小型哺乳动物进行的科罗拉多蜱传热(CTF)实地研究表明,最小花栗鼠和侧纹黄鼠是CTF病毒最重要的宿主,也是蜱媒安德逊革蜱未成熟阶段的病毒来源。其他物种(白足鼠、理查森黄鼠、暗花栗鼠)是次要宿主。啮齿动物中病毒活动的强度因地点而异。在RMNP的冰碛公园地区发现啮齿动物的感染率最高。在海拔3290米以上的彩虹弯道和冻原地区,感染率最低。啮齿动物的感染率在4月至7月保持恒定(捕获动物中有5%-6%出现病毒血症),然后在8月和9月降至1.7%-2.5%,同时若蜱外寄生率下降。捕获了许多同时出现病毒血症和抗体呈阳性的动物。在野外条件下,中和抗体血清转化并不总是发生。

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