Virus-like particles in bovine turbinate cells infected with bovine virus diarrhoea/mucosal disease virus.

Thin sections of bovine turbinate cells grown in culture and infected with the NADL strain of bovine virus diarrhoea/mucosal disease virus have been examined by electron microscopy. Infected cells exhibited ultrastructural modification of the rough endoplasmic reticulum and associated with this small numbers of virus-like particles were observed. Advanced stages of cytopathic effect were illustrated by cells showing a marked increase in electron-density. These features were not observed in uninfected control cultures.