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结节病所致进行性脊髓病

Progressive myelopathy due to sarcoid.

作者信息

Caroscio J T, Yahr M D

出版信息

Clin Neurol Neurosurg. 1980;82(4):217-22. doi: 10.1016/0303-8467(80)90012-8.

DOI:10.1016/0303-8467(80)90012-8
PMID:6263526
Abstract

A patient developed a progressive paraparesis after a bout of uveitis and parotitis; and lung biopsy was diagnostic of sarcoidosis. A myelogram was normal on two occasions. Spinal tap revealed an elevated protein, a pleocytosis and a low glucose, and a diagnosis of sarcoidosis of the spinal cord made. Previous reports of sarcoidosis of the spinal cord are reviewed. Of interest in this case was an elevated CSF IgG. Elevation of CSF globulin or gamma globulin may be a common finding in this condition as it was noted in 14 of 15 cases of CNS sarcoid previously reported.

摘要

一名患者在患葡萄膜炎和腮腺炎后出现进行性截瘫;肺部活检诊断为结节病。脊髓造影两次结果均正常。腰椎穿刺显示蛋白升高、细胞增多和葡萄糖降低,诊断为脊髓结节病。回顾了以往关于脊髓结节病的报告。该病例中值得关注的是脑脊液IgG升高。脑脊液球蛋白或γ球蛋白升高可能是这种疾病的常见表现,如先前报道的15例中枢神经系统结节病中有14例出现这种情况。

相似文献

1
Progressive myelopathy due to sarcoid.结节病所致进行性脊髓病
Clin Neurol Neurosurg. 1980;82(4):217-22. doi: 10.1016/0303-8467(80)90012-8.
2
A Unique Case of Sarcoid-associated Myelopathy Accompanied by Lung Cancer.一例伴有肺癌的结节病相关性脊髓病。
Intern Med. 2023 Dec 1;62(23):3531-3535. doi: 10.2169/internalmedicine.0943-22. Epub 2023 Apr 14.
3
Radiation myelopathy of cervical spinal cord simulating intramedullary neoplasm.模拟髓内肿瘤的颈段脊髓放射性脊髓病
J Neurol Neurosurg Psychiatry. 1974 Oct;37(10):1177-80. doi: 10.1136/jnnp.37.10.1177.
4
[A case of sarcoidosis with simultaneous involvement of the lower brainstem and the whole cervical cord and the extraocular muscles].
Rinsho Shinkeigaku. 2001 Jun;41(6):314-7.
5
Rapid-Onset Thoracic Myelopathy due to an Epidural Sarcoid-Like Lesion in a Pediatric Patient.一名儿科患者因硬膜外类肉瘤样病变导致的快速进展性胸段脊髓病
World Neurosurg. 2018 Mar;111:377-380. doi: 10.1016/j.wneu.2017.12.185. Epub 2018 Jan 8.
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Sarcoidosis of the spinal cord and medulla oblongata. A pathological and neuroradiological case report.脊髓和延髓结节病。一例病理及神经放射学病例报告。
Clin Neuropathol. 1994 Jan-Feb;13(1):19-25.
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[Sarcoidosis revealed by a spinal cord lesion].
Rev Neurol (Paris). 2004 Apr;160(4 Pt 1):452-5. doi: 10.1016/s0035-3787(04)70928-5.
8
Spinal cord sarcoidosis. Case report.脊髓结节病。病例报告。
J Neurosurg. 1984 Nov;61(5):981-2. doi: 10.3171/jns.1984.61.5.0981.
9
[Spinal cord sarcoidosis--diagnostic value of Gd-enhanced MRI].[脊髓结节病——钆增强磁共振成像的诊断价值]
Rinsho Shinkeigaku. 1992 Jun;32(6):631-6.
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Sarcoidosis presenting as progressive myelopathy.以进行性脊髓病为表现的结节病。
Clin Neuropathol. 1988 Mar-Apr;7(2):77-80.

引用本文的文献

1
Sarcoidosis of the spinal cord: literature review and report of eight cases.脊髓结节病:文献综述及八例报告
J Natl Med Assoc. 2006 Jun;98(6):965-76.
2
Subacute myelopathy as the presenting manifestation of sarcoidosis.
Acta Neurochir (Wien). 1982;65(3-4):193-7. doi: 10.1007/BF01405845.
3
Spinal leptomeningeal sarcoidosis.脊髓软脊膜结节病
Neuroradiology. 1987;29(1):100. doi: 10.1007/BF00341053.