Lieb M, Talland C
J Virol. 1981 May;38(2):789-91. doi: 10.1128/JVI.38.2.789-791.1981.
IS5 inserted into gene cI of bacteriophage lambda greatly reduces the synthesis of Rex protein. Two other IS insertions in cI are even more polar, but two amber mutations near the 5' end of cI allow normal expression of Rex.
插入到噬菌体λ基因cI中的IS5大大降低了Rex蛋白的合成。cI中的另外两个IS插入更具极性,但cI 5'端附近的两个琥珀突变允许Rex正常表达。