秀丽隐杆线虫unc-54肌球蛋白重链基因的分子分析。
Molecular analysis of the unc-54 myosin heavy-chain gene of Caenorhabditis elegans.
作者信息
MacLeod A R, Karn J, Brenner S
出版信息
Nature. 1981 Jun 4;291(5814):386-90. doi: 10.1038/291386a0.
DOI:10.1038/291386a0
PMID:6264304
Abstract
The properties of a small internal deletion mutant, E675, have been exploited in the molecular cloning of the unc-54 gene. This mutation uniquely identifies unc-54 sequences as molecules of altered length in E675 and provides a genetic and physical marker for the active gene, its messenger RNA and its protein product.
摘要
一个小的内部缺失突变体E675的特性已被用于unc-54基因的分子克隆。这种突变独特地将unc-54序列识别为E675中长度改变的分子，并为活性基因、其信使RNA及其蛋白质产物提供了遗传和物理标记。
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