Seman G
Oncology. 1981;38(4):204-9. doi: 10.1159/000225552.
Peculiar inclusions, which we call B-bodies, have been observed in cells collected by leukapheresis from patients with acute leukemia. B-bodies, which often have virus-like features, were present in blast cells of 24 (44%)( of the 54 patients examined; in 16 out of 29 with acute myelogenous leukemia, 5 out of 16 with acute lymphoblastic leukemia, 2 out of 3 with undifferentiated leukemia, and 1 out of 2 with myelogenous leukemia in blastic transformation. The ultrastructure of these apparently polymorphic inclusions was always based on a system of of cytoplasmic channels containing dense, axial filaments. Patients with B-bodies were mostly women near menopause (70% of the positives).
在通过白细胞分离术从急性白血病患者采集的细胞中观察到了一种特殊的包涵体，我们将其称为B小体。B小体通常具有病毒样特征，在所检查的54例患者中的24例（44%）的原始细胞中存在；在29例急性髓性白血病患者中的16例、16例急性淋巴细胞白血病患者中的5例、3例未分化白血病患者中的2例以及2例处于原始细胞转化期的髓性白血病患者中的1例中存在。这些明显多形性包涵体的超微结构总是基于一个包含致密轴向细丝的细胞质通道系统。有B小体的患者大多是接近绝经的女性（阳性患者的70%）。
