Greer C A, Mori K, Shepherd G M
Brain Res. 1981 Aug 3;217(2):295-303. doi: 10.1016/0006-8993(81)90005-6.
Studies were carried out on the in vitro turtle olfactory bulb preparation with a modification of the [14C]-2-deoxyglucose (2-DG) technique. Electrical stimulation of either the dorsal or ventral division of the olfactory nerve produced broad bands of activity, spreading across laminae, in the corresponding half of the olfactory bulb. Pretreatment of the isolated preparation in a low calcium bath eliminated focal 2-DG uptake induced by electrical stimulation of the nerve. In contrast, pretreatment with the GABAergic antagonist, bicuculline, produced a notable increase in 2-DG accumulation. These findings are discussed in the light of the topographical innervation of the olfactory bulb by the olfactory nerve as well as the known synaptic organization of the olfactory bulb and the putative neurotransmitters operative in local circuits.
采用改良的[14C]-2-脱氧葡萄糖（2-DG）技术，对离体龟嗅球标本进行了研究。电刺激嗅神经的背侧或腹侧分支，在嗅球相应的半侧产生了广泛的活动带，这些活动带跨越各层。在低钙浴中对离体标本进行预处理，消除了神经电刺激诱导的局灶性2-DG摄取。相反，用GABA能拮抗剂荷包牡丹碱预处理，使2-DG积累显著增加。根据嗅神经对嗅球的拓扑支配以及嗅球已知的突触组织和局部回路中起作用的假定神经递质，对这些发现进行了讨论。
