Sapienza S, Talbi B, Jacquemin J, Albe-Fessard D
Exp Brain Res. 1981;43(1):47-56. doi: 10.1007/BF00238808.
Experiments using the same glass microelectrode (6--8 M omega) for recording and stimulating were performed on 12 rats in which 379 cortical cells were studied in 65 penetrations through the motor and somatosensory cortical zones. To avoid anaesthetic effects the rats were chronically implanted with a head system derived from the one developed by Noda et al. (1971). These animals well accepted head fixation and the peripheral receptive fields could thus be easily investigated. In a preliminary experiment the number of pyramidal cells activated by a given stimulus intensity was evaluated. The lowest threshold intensities were always observed in the Vth pyramidal layer, as well as correspondence between cell input and output. The same type of organization, with identical thresholds, existed in the so-called "Motor" and "Somatosensory" cortical zones. Movements could be obtained when stimulating near non-PT cells (600--700 micron below the cortical surface). However, thresholds were higher at this level and it is thought that the movements were due to a spread of the stimulating current to the pyramidal tract cell layer.
使用同一根玻璃微电极（6 - 8兆欧）进行记录和刺激的实验，在12只大鼠身上进行，通过运动和体感皮层区进行了65次穿刺，研究了379个皮层细胞。为避免麻醉作用，大鼠长期植入了一种源自野田等人（1971年）开发的头部系统。这些动物很好地接受了头部固定，因此可以轻松研究外周感受野。在一个初步实验中，评估了给定刺激强度激活的锥体细胞数量。最低阈值强度总是在第V层锥体细胞层中观察到，以及细胞输入和输出之间的对应关系。在所谓的“运动”和“体感”皮层区存在相同类型的组织，具有相同的阈值。当在靠近非锥体束细胞（皮层表面以下600 - 700微米）处进行刺激时，可以获得运动。然而，这个水平的阈值更高，据认为运动是由于刺激电流扩散到锥体束细胞层所致。
