Dany F, Doutre M S, Coupillaud G, Beylot C, Dallocchio M
Sem Hop. 1981;57(25-28):1223-5.
A 33 years old woman was investigated for paroxystic hypertension worsened by bêta-adrenergic blocking drugs therapy. Clinical investigation revealed cutaneous abnormalities with erythemato-macular eruption on dorsalis faces of both hands. These lesions were histologically non specific with capillaritis and oedema. angiography revealed a left sided pheochromocytoma. Cutaneous abnormalities disappear after intervention. Pheochromocytoma is rarely associated with cutaneous disease: most papers describe intermittent "flush" phenomenon. Permanent lesions are non fréquent: erythrocyanosis, rash with nodosities or macular lesions, restricted places of necorsis, distal necorsis, hypochromic lesions. The variability of cutaneous disease of pheochromocytoma seems reliable to the biochemical structure of catecholamine secreted by tumor.