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来自胸腔积液的乳腺癌“MCF-7细胞系”的组织培养与扫描电子显微镜观察

Tissue culture and scanning electron microscopy of breast carcinoma 'cell line MCF-7' from pleural effusion.

作者信息

Rizk N N, El-Rakhawy M T

出版信息

Acta Anat (Basel). 1981;109(1):70-4. doi: 10.1159/000145367.

DOI:10.1159/000145367
PMID:6266191
Abstract

The surface ultrastructure of tissue-cultured cells derived from the pleural effusion of metastatic scirrhous breast carcinoma in the human MDF-7 cell line was studied by scanning electron microscopy. It was found to form monolayers of various colonies or collections of cells which were either separate or intimately adherent. The surface ultrastructure of the cells was found to be exclusively formed of microvilli. Data suggesting a diagnostic significance of microvilli in cancer cells were discussed. Observations were made which point to the existence of a compensatory absorptive functional activity exerted by the microvilli.

摘要

通过扫描电子显微镜研究了源自人MDF - 7细胞系转移性硬癌性乳腺癌胸腔积液的组织培养细胞的表面超微结构。发现它形成了各种细胞集落或细胞集合的单层,这些细胞要么分离,要么紧密附着。发现细胞的表面超微结构完全由微绒毛形成。讨论了提示微绒毛在癌细胞中具有诊断意义的数据。观察结果表明存在微绒毛发挥的代偿性吸收功能活性。

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