Sarcoidosis of the lacrimal sac.

Two women with acute dacryocystitis were found to have noncaseating granulomatous inflammation of the lacrimal sac and nasal mucosa. One patient had chronic uveitis and the other had skin lesions and generalized lymphadenopathy histologically compatible with sarcoidosis. The diagnosis was supported by elevation of serum levels of angiotensin-converting enzyme. To our knowledge, these are the sixth and seventh histologically confirmed cases of sarcoidosis of the lacrimal sac. They differ from previously reported cases in the absence of classic roentgenographic changes of sarcoidosis. Analysis of all reported cases suggests an association between lacrimal sac and upper respiratory tract sarcoidosis.