一种使用电子捕获检测的气相色谱法，用于测定血液中氟烷、氯仿和三氯乙烯的浓度。

A method of gas chromatography using electron-capture detection for the determination of blood concentrations of halothane, chloroform and trichloroethylene.

作者信息

Davies D D

出版信息

Br J Anaesth. 1978 Feb;50(2):147-55. doi: 10.1093/bja/50.2.147.

DOI:10.1093/bja/50.2.147

Abstract

A method of gas chromatography using electron-capture detection for the determination of the concentration of the halogenated anaesthetic agents halothane, chloroform and trichloroethylene in blood is described. The accuracy of the analysis (measured blood concentration as a percentage of the calculated concentration) was: Halothane (11 blood samples in the range 37.9-6.00 mg/100 ml), mean 100.7 (SD 2.27), range 97.3-104.0; (12 samples in the range 0.164-0.0045 mg/100 ml), mean 98.8 (SD 6.80), range 90.7-111.1. Chloroform (five blood samples in the range 63.6-7.40 mg/100 ml), mean 100.4 (SD 1.30), range 99.3-102.5. Trichloroethylene (five blood samples in the range 20.6-13.2 mg/100 ml), mean 101.6 (SD 1.60), range 99.6-104.0.

摘要

描述了一种采用电子捕获检测的气相色谱法，用于测定血液中卤代麻醉剂氟烷、氯仿和三氯乙烯的浓度。分析的准确度（测量的血液浓度占计算浓度的百分比）为：氟烷（11份血液样本，浓度范围为37.9 - 6.00mg/100ml），平均值100.7（标准差2.27），范围97.3 - 104.0；（12份样本，浓度范围为0.164 - 0.0045mg/100ml），平均值98.8（标准差6.80），范围90.7 - 111.1。氯仿（5份血液样本，浓度范围为63.6 - 7.40mg/100ml），平均值100.4（标准差1.30），范围99.3 - 102.5。三氯乙烯（5份血液样本，浓度范围为20.6 - 13.2mg/100ml），平均值101.6（标准差1.60），范围99.6 - 104.0。