Mottow-Lippa L, Jakobiec F A, Iwamoto T
Ophthalmology. 1981 Jun;88(6):575-80. doi: 10.1016/s0161-6420(81)35001-5.
A 60-year-old woman presented five years after a radical mastectomy for breast carcinoma, with vague, non-specific complaints referable to the left eye, consisting of ptosis, extraocular motility problems, and irritation, all believed initially to be due to an inflammatory causation. The indurated quality of the involved tissues, coupled with the results of computed tomographic studies, led to the suspicion of the correct diagnosis, namely, metastatic scirrhous carcinoma of the ocular adnexa. Biopsy and electron microscopic studies confirmed this diagnosis. Clinical and pathologic pitfalls in failing to distinguish scirrhous carcinoma from an inflammatory lesion are discussed.
一名60岁女性在乳腺癌根治性乳房切除术后五年出现症状，左眼有模糊、非特异性的不适，包括上睑下垂、眼球运动问题和眼刺激感，最初均认为是炎症所致。受累组织的硬结性质，结合计算机断层扫描结果，引发了对正确诊断的怀疑，即眼附属器转移性硬癌。活检和电子显微镜研究证实了这一诊断。文中讨论了未能将硬癌与炎性病变区分开来的临床和病理陷阱。
