雏鸡皮下接种痘疫苗对免疫反应和体重增加的影响。

Effect of subcutaneous pox vaccination of young chicks on immune responses and weight gains.

作者信息

Springer W T, Truman R W

出版信息

Poult Sci. 1981 Jun;60(6):1213-20. doi: 10.3382/ps.0601213.

Abstract

Two fowl pox and two pigeon pox vaccines were administered subcutaneously in the dorsum of the neck of specific-pathogen-free (SPAFAS) chicks at day of hatch in separate studies. Treatment levels used were 1:2, 1:10, or 1:50 dilution of the recommended wing web dose. Both pigeon pox vaccines and one fowl pox vaccine depressed body weight gains significantly by day 14. Mean body weight gains of female chicks were less affected by pigeon pox vaccines than by fowl pox vaccines. The mean hemagglutination-inhibition (HI) antibody titer to Newcastle disease virus (NDV) of chicks given one pigeon pox vaccine at the 1:2 dilution was significantly lower (P less than .01) than titers of sham-treated controls. The number of immunoglobulin-M (IgM) secreting cells in the spleen was significantly less (P less than .05) at day 14 in all pox vaccinated chicks when compared to sham-treated controls.

摘要

在两项独立研究中，于特定病原体清除（SPAFAS）雏鸡出壳当天，在其颈部背侧皮下接种了两种鸡痘疫苗和两种鸽痘疫苗。所使用的处理水平为推荐的翼膜剂量的1:2、1:10或1:50稀释液。到第14天时，两种鸽痘疫苗和一种鸡痘疫苗均显著降低了体重增加。与鸡痘疫苗相比，鸽痘疫苗对雌性雏鸡平均体重增加的影响较小。以1:2稀释度接种一种鸽痘疫苗的雏鸡，其对新城疫病毒（NDV）的平均血凝抑制（HI）抗体效价显著低于（P<0.01）假处理对照组的效价。与假处理对照组相比，在第14天时，所有接种痘苗的雏鸡脾脏中分泌免疫球蛋白M（IgM）的细胞数量显著减少（P<0.05）。