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肾上腺素对慢性牙周炎患者牙龈中前列腺素E2和环磷酸腺苷水平的影响。

Effect of epinephrine on prostaglandin E2 and cyclic AMP levels in gingiva of patients with chronic periodontitis.

作者信息

ElAttar T M, Lin H S, Tira D E

出版信息

Prostaglandins Med. 1981 Jun;6(6):601-12. doi: 10.1016/0161-4630(81)90121-x.

Abstract

The levels of prostaglandin E2 (PGE2) and cyclic AMP (cAMP) in human gingival samples were determined by means of radioimmunoassay after incubation with epinephrine (10(-6)M) at different time intervals. The levels of PGE2 and cAMP reached a maximum in the control and hormone treated samples after 80 and 40 minutes, respectively. Epinephrine seemed to affect a lesser increase in PGE2 and a greater increase in cAMP values in gingival tissues when compared with control samples. When the data were analysed, there was statistically significant differences found between the control and hormone treated samples regarding both PGE2 and cAMP.

摘要

在不同时间间隔与肾上腺素(10⁻⁶M)孵育后,通过放射免疫测定法测定人牙龈样本中前列腺素E2(PGE2)和环磷酸腺苷(cAMP)的水平。在对照样本和激素处理样本中,PGE2和cAMP的水平分别在80分钟和40分钟后达到最大值。与对照样本相比,肾上腺素似乎对牙龈组织中PGE2的增加影响较小,而对cAMP值的增加影响较大。在分析数据时,发现对照样本和激素处理样本在PGE2和cAMP方面均存在统计学上的显著差异。

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