Ivanov A P, Bashkirtsev V N, Tkachenko E A
Vopr Virusol. 1981 Mar-Apr(2):200-3.
The possibility of using ELISA for the detection of arenavirus antigens in different organs of infected newborn white mice as well as in the culture fluids of arenavirus-infected cell cultures was demonstrated. The sensitivity of ELISA in antigen detection 100-200 times exceeds that of the CFT, and the time of antigen detection after inoculation of animals or cell cultures is much shorter. The use of ELISA block for the detection and titration of virus-specific antibody also demonstrated high sensitivity of this method as compared with the CFT.
已证实可使用酶联免疫吸附测定法（ELISA）检测感染新生小白鼠不同器官以及沙粒病毒感染细胞培养物培养液中的沙粒病毒抗原。ELISA在抗原检测方面的灵敏度比补体结合试验（CFT）高100 - 200倍，且在接种动物或细胞培养物后检测抗原的时间要短得多。与CFT相比，使用ELISA阻断法检测和滴定病毒特异性抗体也证明了该方法具有高灵敏度。
