免疫发育疾病的生物化学 - Suppr

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Biochemistry of diseases of immunodevelopment.

作者信息

Martin D W, Gelfand E W

出版信息

Annu Rev Biochem. 1981;50:845-77. doi: 10.1146/annurev.bi.50.070181.004213.

DOI:10.1146/annurev.bi.50.070181.004213

PMID:6267992

Abstract

摘要

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Biochemistry of diseases of immunodevelopment.免疫发育疾病的生物化学

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[Primary immunodeficiencies and purine metabolism].[原发性免疫缺陷与嘌呤代谢]

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Immunodeficiency secondary to adenosine deaminase deficiency and purine nucleoside phosphorylation deficiency.继发于腺苷脱氨酶缺乏和嘌呤核苷磷酸化酶缺乏的免疫缺陷。

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Sp1 is essential for both enhancer-mediated and basal activation of the TATA-less human adenosine deaminase promoter.Sp1对于无TATA框的人类腺苷脱氨酶启动子的增强子介导激活和基础激活均至关重要。

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