Tareyeva I E, Filimonova R G, Fadeeva L L, Khaletskaya E V, Nevraeva E G
Clin Nephrol. 1981 Mar;15(3):115-8.
Antiviral activity was evaluated in sera from 65 patients with chronic glomerulonephritis (GN), 58 patients with SLE and 59 healthy controls. Antibodies to influenza A2 and B, and parainfluenza I-II-III viruses occurred much more frequently in GN than in healthy controls. Geometric mean antibody titers to measles, influenza A2 and B, and parainfluenza I-II-III were found to be elevated. The frequency of antiviral antibodies and their level in GN patients were similar to those in SLE patients. Detection of increased antiviral activity in sera of patients with chronic GN extends the range of diseases where persistent latent viral infection may be relevant.
对65例慢性肾小球肾炎（GN）患者、58例系统性红斑狼疮（SLE）患者和59名健康对照者的血清进行了抗病毒活性评估。与健康对照者相比，GN患者中甲型和乙型流感病毒以及副流感病毒Ⅰ - Ⅱ - Ⅲ型抗体的出现频率要高得多。发现麻疹、甲型和乙型流感病毒以及副流感病毒Ⅰ - Ⅱ - Ⅲ型的几何平均抗体滴度升高。GN患者中抗病毒抗体的频率及其水平与SLE患者相似。在慢性GN患者血清中检测到抗病毒活性增加，扩大了可能与持续性潜伏病毒感染相关的疾病范围。
