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[脑部血管疾病中红细胞结构功能特性的变化]

[Changes in the structuro-functional properties of erythrocytes in vascular diseases of the brain].

作者信息

Mkheian E E, Tunian Iu S, Akopov S E, Badzhinian S A, Bakunts G O

出版信息

Vopr Med Khim. 1981;27(4):486-8.

PMID:6270906
Abstract

In patients with various impairments of brain circulation a decrease in deformation and osmotic stability of erythrocytes were observed. These findings correlated with the decrease in activity of Na+, K+- and Ca2+-ATPases from the cell membranes. At the same time, the Mg/+-ATPase activity was markedly increased. Conductivity for K+, Na+ and Ca2+ was increased in lipid bilayer of erythrocytes obtained from the patients with brain vascular pathology.

摘要

在各种脑循环障碍患者中,观察到红细胞变形性和渗透稳定性降低。这些发现与细胞膜上Na+、K+-和Ca2+-ATP酶活性降低相关。同时,Mg2+-ATP酶活性显著增加。从脑血管病变患者获得的红细胞脂质双层中,K+、Na+和Ca2+的电导率增加。

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