Menges V
Z Lymphol. 1981 Jul;5(1):13-20.
Since microcalcifications occur in mammary carcinoma in a quite specific manner and above all very early, i.e. long before an infiltrative focal shadow can be recognized in the mammogram, the microcalcifications have proved to be a significant and in many cases the only early symptom of small, clinically still occult mammary carcinomas. On the basis of microcalcifications, we are so far been able to detect a total of 220 clinically unequivocal occult small and very small mammary carcinomas with an average tumor size of 6 X 8 mm, and were thus able to apply the necessary and decisive early therapy. Today, microcalcifications enable us to detect to an increasing extent even preinvasive stages of mammary carcinoma and also to verify them by biopsy.
由于微钙化在乳腺癌中以非常特殊的方式出现,而且最重要的是出现得非常早,即在乳房X光片中能够识别出浸润性局灶性阴影之前很久就已出现,因此微钙化已被证明是小的、临床上仍隐匿的乳腺癌的一个重要且在许多情况下是唯一的早期症状。基于微钙化,到目前为止我们总共检测出220例临床上明确的隐匿性小乳腺癌和非常小的乳腺癌,平均肿瘤大小为6×8毫米,从而能够实施必要且关键的早期治疗。如今,微钙化使我们能够越来越多地检测出乳腺癌的甚至是浸润前阶段,并且还能通过活检对其进行验证。