Martinevskiĭ I L, Arakelian I S
Antibiotiki. 1981 Sep;26(9):687-9.
Investigation of the response to polymyxin of 65 strains of Pasteurella isolated from various foci and 46 their back mutants showed that all of them were usually highly resistant to polymyxin (MIC 200--500 micrograms/ml). The Pasteurella strains isolated in the Gissaro-Darvaz natural focus, Turkey and Congo were highly sensitive to polymyxin (MIC 10--25 micrograms/ml). Single cultures highly sensitive to the antibiotic were detected among the polymyxin-resistant strains. Polymyxin-sensitive mutants of these cultures with lowered requirements in the growth factors were obtained.
对从不同疫源地分离出的65株巴氏杆菌及其46株回复突变株对多粘菌素的反应进行研究表明，它们通常对多粘菌素具有高度抗性（最低抑菌浓度为200 - 500微克/毫升）。在吉萨尔 - 达尔瓦兹自然疫源地、土耳其和刚果分离出的巴氏杆菌菌株对多粘菌素高度敏感（最低抑菌浓度为10 - 25微克/毫升）。在多粘菌素抗性菌株中检测到对该抗生素高度敏感的单培养物。获得了这些培养物中对生长因子需求降低的多粘菌素敏感突变体。
