正常人血清中Gm(1)抗体的理化及免疫学特性
The physiochemical and immunological characterization of Gm (1) antibodies from normal human serum.
作者信息
Dival G B, Khalap S
出版信息
Immunology. 1976 Nov;31(5):821-5.
Abstract
The mol. wt and charge characteristics of Gm(1) antibodies from normal human serum were studied by gel filtration and DEAE- anion exchange chromatography. The effect on anti-Gm(1) activity, of incubating individual antisera with disulphide reducing agents, and with anti-IgG or anti-IgM immunoabsorbents were also studied. The results demonstrate the existence of a low molecular weight IgM protein with anti-Gm(1) activity.
摘要
通过凝胶过滤和DEAE-阴离子交换色谱法研究了正常人血清中Gm(1)抗体的分子量和电荷特性。还研究了用二硫键还原剂、抗IgG或抗IgM免疫吸附剂孵育个体抗血清对抗Gm(1)活性的影响。结果表明存在一种具有抗Gm(1)活性的低分子量IgM蛋白。
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The physiochemical and immunological characterization of Gm (1) antibodies from normal human serum.
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本文引用的文献
1
A Low Molecular Weight Immunoglobulin Antigenically Related to 19 S IgM.
J Clin Invest. 1967 Aug;46(8):1329-37. doi: 10.1172/JCI105625.
2
[The human antiglobulins present in the serums of normal subjects. II. Frequency and serologic characteristics].
Rev Hematol. 1960 Jan-Mar;15:40-51.
3
GM GENES AND GAMMA-G-GLOBULIN SYNTHESIS IN THE HUMAN FETUS.
J Immunol. 1965 Apr;94:514-20.
4
ANTIBODY TO HEREDITARY HUMAN GAMMA-GLOBULIN (GM) FACTOR RESULTING FROM MATERNAL-FETAL INCOMPATIBILITY.
Science. 1964 Jul 10;145(3628):170-1. doi: 10.1126/science.145.3628.170.
5
Antibodies to genetic types of gamma globulin after multiple transfusions.
Science. 1963 Feb 1;139(3553):418-9. doi: 10.1126/science.139.3553.418.
6
Hereditary globulin factors and immune tolerance in man.
Science. 1963 Apr 19;140(3564):303-4. doi: 10.1126/science.140.3564.303.
7
Possible origins of the anti-Gm sera.
Nature. 1960 Dec 24;188:1120-1. doi: 10.1038/1881120c0.
8
A new type in the Gm system.
Acta Pathol Microbiol Scand. 1959;45(4):357-70. doi: 10.1111/j.1699-0463.1959.tb04721.x.
9
Dissociation of human serum macroglobulins.
Science. 1957 Mar 29;125(3248):600-1. doi: 10.1126/science.125.3248.600.
10
Agglutination of erythrocytes coated with incomplete anti-Rh by certain rheumatoid arthritic sera and some other sera; the existence of human serum groups.
Acta Pathol Microbiol Scand. 1956;39(3):195-7.
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