正常人血清中Gm(1)抗体的理化及免疫学特性
The physiochemical and immunological characterization of Gm (1) antibodies from normal human serum.
作者信息
Dival G B, Khalap S
出版信息
Immunology. 1976 Nov;31(5):821-5.
Abstract
The mol. wt and charge characteristics of Gm(1) antibodies from normal human serum were studied by gel filtration and DEAE- anion exchange chromatography. The effect on anti-Gm(1) activity, of incubating individual antisera with disulphide reducing agents, and with anti-IgG or anti-IgM immunoabsorbents were also studied. The results demonstrate the existence of a low molecular weight IgM protein with anti-Gm(1) activity.
摘要
通过凝胶过滤和DEAE-阴离子交换色谱法研究了正常人血清中Gm(1)抗体的分子量和电荷特性。还研究了用二硫键还原剂、抗IgG或抗IgM免疫吸附剂孵育个体抗血清对抗Gm(1)活性的影响。结果表明存在一种具有抗Gm(1)活性的低分子量IgM蛋白。
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The physiochemical and immunological characterization of Gm (1) antibodies from normal human serum.正常人血清中Gm(1)抗体的理化及免疫学特性
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