Armour J A, Hopkins D A
J Comp Neurol. 1981 Oct 20;202(2):169-84. doi: 10.1002/cne.902020204.
Cardiac nerves were identified physiologically and injected with horseradish peroxidase in 38 dogs. Retrogradely labeled neurons were present in the greatest number in the middle cervical ganglion, whereas fewer labeled neurons were present in the stellate ganglion. Only occasional neurons in the superior cervical ganglion were labeled, and no labelphysiologically and injected with horseradish peroxidase in 38 dogs. Retrogradely labeled neurons were present in the greatest number in the middle cervical ganglion, whereas fewer labeled neurons were present in the stellate ganglion. Only occasional neurons in the superior cervical ganglion were labeled, and no labelphysiologically and injected with horseradish peroxidase in 38 dogs. Retrogradely labeled neurons were present in the greatest number in the middle cervical ganglion, whereas fewer labeled neurons were present in the stellate ganglion. Only occasional neurons in the superior cervical ganglion were labeled, and no labeled cells were found in the T3 to T6 paravertebral ganglia or in the ganglia contralateral to the nerve injected. following injections into specific cardiac nerves, retrograde labeling was widespread within the middle cervical ganglion, and the distributions of labeled neurons from different nerves overlapped considerably. In the middle cervical ganglion there was little or no regional grouping of cells projecting to specific cardiac nerves. within the stellate ganglion, however, te cardiac-sympathetic cells were clustered primarily at the cranial pole near toe origin of the ventral and dorsal ansae. Mediastinal ganglia and ganglia located in cardiac nerves were frequently as heavily labeled as the ipsilateral stellate ganglion. The occurrence of heavy labeling in mediastinal and cardiac nerve ganglia indicates that these hitherto unreported ganglia play a significant role in cardiac neural regulation. These data imply that the organization of sympathetic neurons controlling the heart is much more complex than has previously been considered.
在38只犬中对心脏神经进行了生理学鉴定并注射辣根过氧化物酶。逆行标记的神经元在颈中神经节中数量最多，而在星状神经节中的标记神经元较少。颈上神经节中仅有偶尔的神经元被标记，在T3至T6椎旁神经节或注射神经对侧的神经节中未发现标记细胞。在向特定心脏神经注射后，逆行标记在颈中神经节内广泛分布，来自不同神经的标记神经元分布有相当大的重叠。在颈中神经节中，投射到特定心脏神经的细胞几乎没有或没有区域分组。然而，在星状神经节内，心脏交感神经细胞主要聚集在靠近腹侧和背侧袢起始处的颅极。纵隔神经节和位于心脏神经中的神经节的标记程度常常与同侧星状神经节一样重。纵隔和心脏神经节中出现重度标记表明这些迄今未报道的神经节在心脏神经调节中起重要作用。这些数据表明，控制心脏的交感神经元的组织比以前认为的要复杂得多。
