Rolland P H, Martin P M
J Gynecol Obstet Biol Reprod (Paris). 1981;10(4):295-305.
To investigate the basic characteristics of PG synthesis by human breast tumors, we have examined the relationship that could exist between the PG production and the morphological, cellular and biochemical characteristics which actually constitute the criteria of diagnosis and prognosis of human breast cancer. The results that are discussed here show that raised PG production would seem to be a marker for neoplastic cells that are capable of leading to metastatic growths in the lymph nodes. The raised production of PG can be a marker of a cell population that has the capacity to be autonomous and which possesses a high potential for metastasis.
为了研究人类乳腺肿瘤中蛋白聚糖（PG）合成的基本特征，我们检测了PG产生与形态学、细胞及生化特征之间可能存在的关系，这些特征实际上构成了人类乳腺癌诊断和预后的标准。此处所讨论的结果表明，PG产生增加似乎是能够导致淋巴结转移性生长的肿瘤细胞的一个标志物。PG产生增加可能是具有自主能力且转移潜力高的细胞群体的一个标志物。
