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Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets.

作者信息

Yamamoto H, Uchigata Y, Okamoto H

出版信息

Nature. 1981 Nov 19;294(5838):284-6. doi: 10.1038/294284a0.

DOI:10.1038/294284a0
PMID:6272129
Abstract
摘要

相似文献

1
Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets.
Nature. 1981 Nov 19;294(5838):284-6. doi: 10.1038/294284a0.
2
DNA strand breaks and poly(ADP-ribose) synthetase activation in pancreatic islets--a new aspect to development of insulin-dependent diabetes and pancreatic B-cell tumors.胰岛中的DNA链断裂与聚（ADP-核糖）合成酶激活——胰岛素依赖型糖尿病和胰腺β细胞瘤发生发展的新视角
Princess Takamatsu Symp. 1983;13:297-308.
3
Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets.
Biochem Biophys Res Commun. 1980 Jul 16;95(1):474-81. doi: 10.1016/0006-291x(80)90762-7.
4
Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.超氧化物歧化酶、过氧化氢酶和聚（ADP - 核糖）合成酶抑制剂对四氧嘧啶和链脲佐菌素诱导的胰岛DNA链断裂以及对胰岛素原合成抑制的保护作用。
J Biol Chem. 1982 Jun 10;257(11):6084-8.
5
Effect of poly(ADP-ribose) synthetase inhibitor administration to rats before and after injection of alloxan and streptozotocin on islet proinsulin synthesis.在给大鼠注射四氧嘧啶和链脲佐菌素之前及之后给予聚（ADP - 核糖）合成酶抑制剂对胰岛胰岛素原合成的影响。
Diabetes. 1983 Apr;32(4):316-8. doi: 10.2337/diab.32.4.316.
6
The role of poly(ADP-ribose) synthetase in the development of insulin-dependent diabetes and islet B-cell regeneration.聚（ADP - 核糖）合成酶在胰岛素依赖型糖尿病发展及胰岛B细胞再生中的作用。
Biomed Biochim Acta. 1985;44(1):15-20.
7
Induction of rat pancreatic B-cell tumors by the combined administration of streptozotocin or alloxan and poly(adenosine diphosphate ribose) synthetase inhibitors.通过联合给予链脲佐菌素或四氧嘧啶与聚（二磷酸腺苷核糖）合成酶抑制剂诱导大鼠胰腺β细胞肿瘤
Cancer Res. 1985 Apr;45(4):1845-9.
8
DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin.
Biochem Biophys Res Commun. 1981 Dec 15;103(3):1014-20. doi: 10.1016/0006-291x(81)90910-4.
9
Streptozotocin, but not alloxan, induces DNA repair synthesis in mouse pancreatic islets in vitro.链脲佐菌素而非四氧嘧啶可在体外诱导小鼠胰岛中的DNA修复合成。
Diabetologia. 1983 Nov;25(5):444-7. doi: 10.1007/BF00282526.
10
Mechanisms of streptozotocin- and alloxan-induced damage in rat B cells.链脲佐菌素和四氧嘧啶诱导大鼠B细胞损伤的机制。
Diabetologia. 1984 Dec;27(6):587-91. doi: 10.1007/BF00276973.

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Hyperglycemia-independent neonatal streptozotocin-induced retinopathy (NSIR) in rats.
大鼠中与高血糖无关的新生期链脲佐菌素诱导的视网膜病变（NSIR）
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Insights into Gastrointestinal Redox Dysregulation in a Rat Model of Alzheimer's Disease and the Assessment of the Protective Potential of D-Galactose.阿尔茨海默病大鼠模型中胃肠道氧化还原失调的见解及D-半乳糖保护潜力的评估
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Desert date seed extract-loaded chitosan nanoparticles ameliorate hyperglycemia and insulin deficiency through the reduction in oxidative stress and inflammation.荒漠枣种子提取物负载壳聚糖纳米粒通过降低氧化应激和炎症改善高血糖和胰岛素缺乏。
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Streptozotocin-Induced Diabetes in a Mouse Model (BALB/c) Is Not an Effective Model for Research on Transplantation Procedures in the Treatment of Type 1 Diabetes.链脲佐菌素诱导的小鼠（BALB/c）糖尿病模型并非用于研究1型糖尿病治疗中移植程序的有效模型。
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Okamoto model for necrosis and its expansions, CD38-cyclic ADP-ribose signal system for intracellular Ca mobilization and Reg (Regenerating gene protein)-Reg receptor system for cell regeneration.冈本模型的坏死及其扩展、CD38-cyclic ADP-ribose 信号系统用于细胞内 Ca 动员，以及 Reg（再生基因蛋白）-Reg 受体系统用于细胞再生。
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