Connell J M
Postgrad Med J. 1981 Aug;57(670):516-7. doi: 10.1136/pgmj.57.670.516.
A case of Graves' disease with potassium perchorate for 22 years without ill effect is described. Thyrotoxicosis recurred 4 weeks after the medication was withdrawn, suggesting that euthyroidism had been maintained by chronic use of the drug. As toxicity of perchlorate is probably dose related, it is suggested that long-term use of low dose perchlorate may be no more hazardous than alternative antithyroid therapy.
本文描述了一例格雷夫斯病患者服用高氯酸钾22年且无不良影响的病例。停药4周后甲状腺毒症复发，提示长期使用该药维持了甲状腺功能正常。由于高氯酸盐的毒性可能与剂量有关，因此建议长期使用低剂量高氯酸盐可能并不比其他抗甲状腺治疗更具危险性。
