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硫必利治疗老年人神经和精神疾病(作者译)

[Tiapride in the treatment of neurological and psychiatric disorders in the elderly (author's transl)].

作者信息

Miletto G, Julou M

出版信息

Sem Hop. 1981;57(43-44):1833-6.

PMID:6274032
Abstract

One hundred patients, aged between 60 and 92 years, were treated with tiapride for neurological disorders (abnormal movements, buccofacial dyskinesias, dopa therapy complications, ballism, eyelid tics, senile tremor, post-traumatic headache, delirium tremens), psychiatric disorders with more or less marked agitation and of various types (hysteria, depression, mood disturbances, hypochondria, delusions, hallucinations), or for mental deficiency, senile dementia, or arteriopathic dementia. Results were excellent, being satisfactory in 70 p. cent, and even more marked in some groups. Tolerance was very good, with some rare cases of somnolence. The efficacy and safety of tiapride makes it of particular value for treating neuropsychiatric disorders in geriatric patients.

摘要

100名年龄在60至92岁之间的患者接受了硫必利治疗,治疗的病症包括神经疾病(异常运动、口面部运动障碍、多巴治疗并发症、颤搐、眼睑抽搐、老年性震颤、创伤后头痛、震颤谵妄)、伴有不同程度明显激动情绪的各类精神疾病(癔症、抑郁症、情绪障碍、疑病症、妄想、幻觉),或用于治疗智力缺陷、老年性痴呆或动脉病性痴呆。结果极佳,70%的患者情况令人满意,在某些组中效果更为显著。耐受性非常好,仅有一些罕见的嗜睡病例。硫必利的疗效和安全性使其在治疗老年患者的神经精神疾病方面具有特殊价值。

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