Di Pietro S, Azzarelli A, Merson M
Tumori. 1981 Oct 31;67(5):437-41. doi: 10.1177/030089168106700508.
At the Istituto Nazionale Tumori of Milan, in its Outpatient Department, 1302 breast surgical biopsies were carried out in 1978. Fibroadenomas occurred in 44.2% and benign dysplasias in 39.3%. Sixty-two cancers (4.8%) and 23 atypical hyperplasias (1.8%) were unexpected findings, with an increasing incidence in women over 50. Seventy-nine duct resections were performed for significant nipple discharge and revealed 5 unexpected carcinomas and 28 papillomas or papillomatosis. In our opinion and experience, this procedure of performing breast biopsy in the presence of a solid lump in women over 30 without hospitalization improves early detection of cancer, lowers costs, cuts down admission waiting lists and increases the number of women who better accept a surgical diagnosis and treatment.
1978年，在米兰国立肿瘤研究所门诊部进行了1302例乳腺手术活检。纤维腺瘤占44.2%，良性发育异常占39.3%。意外发现62例癌症（4.8%）和23例非典型增生（1.8%），50岁以上女性的发病率呈上升趋势。因乳头大量溢液进行了79例导管切除术，其中发现5例意外癌和28例乳头状瘤或乳头状瘤病。根据我们的观点和经验，对于30岁以上有实性肿块的女性在不住院的情况下进行乳腺活检的这种做法，提高了癌症的早期检测率，降低了成本，减少了入院等待名单，并增加了更能接受手术诊断和治疗的女性人数。
