Le Bodic M F, Degott C, Barrier J, Chekroun G, Gaillard F, Couprie F, Mussini-Montpellier J
Sem Hop. 1982 Mar 4;58(9):547-53.
The authors report two cases of gold-salt-induced cholestasis. They make a review of the thirteen cases previously related in the literature ; the cholestasis was constant, the hepatocytic necrosis was unusual and the gold-salts were difficult to visualize in the liver biopsy and more especially at the ultrastructural level. The immunological mechanism of hypersensibility is well established ; the possibility of an associated hepatotoxicity is debated.
作者报告了两例金盐诱导的胆汁淤积病例。他们回顾了文献中先前报道的13例病例；胆汁淤积是持续存在的，肝细胞坏死并不常见，并且在肝活检中，尤其是在超微结构水平上，金盐很难被观察到。超敏反应的免疫机制已得到充分证实；关于是否存在相关肝毒性的可能性仍存在争议。
