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急性肺栓塞导致的胆汁淤积和肝细胞坏死（作者译）

[Cholestasis and liver cell necrosis resulting from acute pulmonary embolism (author's transl)].

作者信息

Beckert W

出版信息

Z Erkr Atmungsorgane. 1981;156(2):184-92.

PMID:7257449
Abstract

124 autopsy cases with acute pulmonary embolism were investigated. Severe or moderate necrosis of parenchymal cells were found in 24%, and disseminating microfocal necrosis furthermore in 32%. An unsignificant or mild cholestasis was observed in 44%. The cause of necrotic liver damage is a complex circulatory disturbance, formed by acinar liver structure. A correlation between degree of thromboembolism and liver necrosis or cholestasis does not exist.

摘要

对124例急性肺栓塞尸检病例进行了研究。发现24%的病例存在实质细胞重度或中度坏死，另有32%存在弥漫性微灶性坏死。44%的病例观察到无明显或轻度胆汁淤积。坏死性肝损伤的原因是由肝腺泡结构形成的复杂循环障碍。血栓栓塞程度与肝坏死或胆汁淤积之间不存在相关性。

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