Mann J M, Ahtone J L
Am Fam Physician. 1982 Mar;25(3):129-32.
Hepatitis A is a common communicable disease in this country. Each diagnosed case of hepatitis A involves the problem of selecting contacts for post-exposure immunoglobulin. These decisions should be systematic, based on current knowledge of epidemiology, kinetics of viral excretion by infected persons and the influence of time on the efficacy of immunoglobulin prophylaxis. An algorithm incorporates this information into a strategy consistent with the United States Public Health Service guidelines.
甲型肝炎在该国是一种常见的传染病。每一例确诊的甲型肝炎病例都涉及到为接触者选择暴露后免疫球蛋白的问题。这些决策应该是系统的,基于当前的流行病学知识、感染者病毒排泄的动力学以及时间对免疫球蛋白预防效果的影响。一种算法将这些信息整合到一种与美国公共卫生服务指南相一致的策略中。