Podobiński M, Kajewska B
Med Pr. 1981;32(5):331-5.
The studies covered 32 workers chronically exposed to CS2 and controls. In all subjects diethyldithiocarbamaturia was evaluated and J131 labelled Bengal Rouge decay half-time was determined. The studies indicated statistically significantly lower DDC excretion in CS2 exposed workers, as compared to controls. On the other hand no statistically significant differences were found at the Bengal rouge decay half--time in blood. The above studies suggest that the disulphuran metabolic route was impaired prior to the occurrence of the changes in liver blood flow of CS2 exposed workers.
这些研究涵盖了32名长期接触二硫化碳的工人以及对照组。对所有受试者评估了二乙基二硫代氨基甲酸盐尿症，并测定了131J标记的孟加拉红衰变半衰期。研究表明，与对照组相比，接触二硫化碳的工人二乙基二硫代氨基甲酸盐排泄量在统计学上显著降低。另一方面，血液中孟加拉红衰变半衰期未发现统计学上的显著差异。上述研究表明，在接触二硫化碳的工人肝脏血流出现变化之前，二硫化碳代谢途径就已经受损。
