[Molecular mechanisms of stabilization and preparation of metabolic breaks in DNA strands in vivo. I. Tandem action of exonuclease V and DNA polymerase II].

Investigation of the formation of metabolic imbalance breaks in the DNA of thy- cells of E. coli during thymine starvation is described. The results of experiments indicate that two enzymes--exonuclease V and 3' exonuclease activity of DNA polymerase II take part in the formation of metabolic imbalance gaps. The manifestation of activity of the enzymes has a tandem character.