头孢尼西、头孢唑肟和青霉素对B组链球菌的体外杀菌活性比较
Comparative in vitro bactericidal activity of cefonicid, ceftizoxime, and penicillin against group B streptococci.
作者信息
Bayer A S, Morrison J O, Kim K S
出版信息
Antimicrob Agents Chemother. 1982 Feb;21(2):344-6. doi: 10.1128/AAC.21.2.344.
Abstract
The minimal inhibitory and bactericidal concentrations for 108 group B streptococcal strains were determined for two new cephalosporins, cefonicid and ceftizoxime, and compared to those of penicillin G. Penicillin G was the most active inhibitory and bactericidal agent. Ceftizoxime was a significantly more active inhibitory and bactericidal agent than cefonicid (P less than 0.0005, P less than 0.025, respectively.
摘要
测定了两种新型头孢菌素头孢尼西和头孢唑肟对108株B族链球菌的最低抑菌浓度和最低杀菌浓度，并与青霉素G进行比较。青霉素G是最有效的抑菌和杀菌药物。头孢唑肟作为抑菌和杀菌药物的活性明显高于头孢尼西（分别P<0.0005，P<0.025）。
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