Baker C J, Webb B J, Barrett F F
Antimicrob Agents Chemother. 1976 Jul;10(1):128-31. doi: 10.1128/AAC.10.1.128.
The minimal inhibitory concentration of 10 antibiotics for 244 isolates of group B streptococci was determined. Susceptibility to penicillin G, ampicillin, cephalothin, chloramphenicol, and carbenicillin was uniform. Tetracycline and bacitracin resistance among these isolates was frequent (87.5 and 97.9%, respectively). Three strains (1.2%) failed to be inhibited by 100 mug of lincomycin or clindamycin per ml. Susceptibility of these 244 strains to the agents tested was unrelated to source of the isolate, year of isolation, or strain serotype. No apparent change in the suceptibility of group B streptococci to penicillin G has occurred during the past 2 decades.
测定了10种抗生素对244株B族链球菌的最低抑菌浓度。这些菌株对青霉素G、氨苄西林、头孢噻吩、氯霉素和羧苄西林的敏感性一致。四环素和杆菌肽耐药在这些分离株中很常见(分别为87.5%和97.9%)。三株菌株(1.2%)每毫升100微克的林可霉素或克林霉素未能抑制。这244株菌株对所测试药物的敏感性与分离株来源、分离年份或菌株血清型无关。在过去20年中,B族链球菌对青霉素G的敏感性没有明显变化。