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正常、精神分裂症、抑郁、躁狂和厌食症患者脑脊液中β-内啡肽免疫反应性

CSF beta-endorphin-immunoreactivity in normal, schizophrenic, depressed, manic and anorexic subjects.

作者信息

Gerner R H, Sharp B

出版信息

Brain Res. 1982 Apr 8;237(1):244-7. doi: 10.1016/0006-8993(82)90574-1.

DOI:10.1016/0006-8993(82)90574-1
PMID:6280804
Abstract

beta-Endorphin immunoreactivity was measured in cerebrospinal fluid of 75 medication-free subjects: normal, depressed, schizophrenic, and anorexic. No significant differences in beta-endorphin immunoreactivity were found. Affinity extraction chromatography revealed beta-lipotropin and beta-endorphin, but no apparent precursors.

摘要

在75名未服用药物的受试者（正常、抑郁、精神分裂症和厌食症患者）的脑脊液中测量了β-内啡肽免疫反应性。未发现β-内啡肽免疫反应性有显著差异。亲和提取色谱法显示有β-促脂解素和β-内啡肽，但没有明显的前体。

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