Zamoskovskiĭ E M, Darinskiĭ Iu A, Merkulova O S
Fiziol Zh SSSR Im I M Sechenova. 1982 Feb;68(2):199-205.
The prolonged high-frequency synaptic activation of the frog spinal motoneurons suppressing their firing, leads to an increase in the size of synapses and to a considerable shift in their ultrastructure. Restoration of the functional and morphological alterations in the cells after cessation of their rhythmical activation proceeds with different speed: the restoration of neurons' ability to generate synaptic and spike potentials in response to testing stimulation of afferents occurs much earlier than the restoration of the cells' ultrastructure and size. Neurons with obviously changed ultrastructure of soma and synaptic apparatus are capable of generating synaptic and spike potentials in response to stimulation. At the same time, the size of the neurons returns to normal either than the normalizing of cell ultrastructures whose speed of restoration varies as well.
青蛙脊髓运动神经元的高频突触激活持续时间延长会抑制其放电,导致突触大小增加及其超微结构发生显著变化。在节律性激活停止后,细胞功能和形态改变的恢复速度不同:神经元在接受传入测试刺激时产生突触电位和锋电位的能力恢复得比细胞超微结构和大小的恢复要早得多。胞体和突触装置超微结构明显改变的神经元能够对刺激产生突触电位和锋电位。与此同时,神经元的大小恢复正常,而细胞超微结构的恢复速度也各不相同,其恢复正常的时间则有所不同。