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颌下腺腺样囊性癌

Adenoid cystic carcinoma of the submaxillary gland.

作者信息

Belson T P, Toohill R J, Lehman R H, Chobanian S L, Grossman T W, Malin T C

出版信息

Laryngoscope. 1982 May;92(5):497-501. doi: 10.1288/00005537-198205000-00007.

DOI:10.1288/00005537-198205000-00007
PMID:6281595
Abstract

A review of submaxillary gland neoplasms over a 21 year period revealed 15 malignancies and 7 benign tumors. All of the malignancies occurred in females, and 11 of these were adenoid cystic carcinoma. Two of the 11 were found to have infiltrating ductal carcinoma of the breast (1 pre and 1 postdiagnosis of the submaxillary carcinoma) and 3 had benign breast disease. While previous reports have suggested an association of parotid gland neoplasia and breast cancer, this is the first known report of an association between adenoid cystic carcinoma of the submaxillary gland and cancer of the breast. The discussion of adenoid cystic carcinoma of the submaxillary gland emphasizes the increased frequency of this disease in females, its association with breast disease, and also experimental submaxillary gland neoplasia.

摘要

一项对21年间颌下腺肿瘤的回顾显示,有15例恶性肿瘤和7例良性肿瘤。所有恶性肿瘤均发生在女性身上,其中11例为腺样囊性癌。在这11例中,有2例被发现患有乳腺浸润性导管癌(1例在颌下癌诊断前,1例在诊断后),3例患有良性乳腺疾病。虽然先前的报告表明腮腺肿瘤与乳腺癌之间存在关联,但这是已知的第一份关于颌下腺腺样囊性癌与乳腺癌之间关联的报告。对颌下腺腺样囊性癌的讨论强调了这种疾病在女性中发病率的增加、其与乳腺疾病的关联以及实验性颌下腺肿瘤形成。

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