Csaba G, Bohdaneczky E
Acta Physiol Acad Sci Hung. 1981;58(1):15-20.
In the 9-day cultures of liver cells isolated from newborn rats epinephrine was found to increase the number of glycogen containing cells, and caused an elevation of the glycogen content of individual liver cells. Insulin treatment had a weak effect on the number of glycogen containing cells and its effect on intracellular glycogen content was negligible. The experiments indicate that the epinephrine receptor develops in the fetal period and is reactive in the newborn animal, while the insulin receptor is not. It was remarkable that in this period of life and under in vitro conditions the effect on cellular glycogen deposition of epinephrine and insulin is similar.
在从新生大鼠分离的肝细胞进行的9天培养中，发现肾上腺素可增加含糖原细胞的数量，并导致单个肝细胞的糖原含量升高。胰岛素处理对含糖原细胞的数量影响微弱，其对细胞内糖原含量的影响可忽略不计。实验表明，肾上腺素受体在胎儿期发育并在新生动物中具有反应性，而胰岛素受体则不然。值得注意的是，在生命的这个阶段以及体外条件下，肾上腺素和胰岛素对细胞糖原沉积的影响是相似的。
