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尼日利亚拉各斯学童中年龄与对结核菌纯蛋白衍生物(PPD-S)和非典型分枝杆菌抗原致敏之间的关系。

The relationship between age and sensitization to PPD-S and atypical mycobacterial antigens among school children in Lagos, Nigeria.

作者信息

Ogunmekan D A

出版信息

Afr J Med Med Sci. 1980 Mar-Jun;9(1-2):15-20.

PMID:6282081
Abstract

A random sample of school children was tested with PPD-S and one of the following antigens simultaneously namely PPD-F, PPD-G, PPD-PL, and PPD-A. The antigens were prepared from the human tubercle bacillus, Mycobacterium Fortuitum, M. Kansasii the Gause Organism, M. Marinum and M. avium respectively. It was observed that for those who had had no BCG, age had a significant effect on the induration size to PPD-S. The age effect was a linear regression effect, the F for regression being significant at the 1% level. The regression coefficient was found to be 0.4 and the equation to the regression line was Y = -0.6 + 0.4X where X is age and Y is induration size. For all the other antigens, age had no significant effect on the size of induration.

摘要

对一组随机抽取的学童同时进行结核菌素纯蛋白衍生物-S(PPD-S)以及以下抗原之一的检测,这些抗原分别是PPD-F、PPD-G、PPD-PL和PPD-A。这些抗原分别由人结核杆菌、偶然分枝杆菌、堪萨斯分枝杆菌(高斯氏菌)、海分枝杆菌和鸟分枝杆菌制备而成。据观察,对于那些未接种卡介苗的儿童,年龄对PPD-S的硬结大小有显著影响。年龄效应呈线性回归效应,回归F值在1%水平上具有显著性。回归系数为0.4,回归线方程为Y = -0.6 + 0.4X,其中X为年龄,Y为硬结大小。对于所有其他抗原,年龄对硬结大小无显著影响。

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