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革兰氏阳性球菌对各种抗生素的敏感性,包括头孢噻肟、氧哌嗪青霉素和N-甲酰亚胺基硫霉素。

Susceptibility of gram-positive cocci to various antibiotics, including cefotaxime, moxalactam, and N-formimidoyl thienamycin.

作者信息

Cherubin C E, Corrado M L, Sierra M F, Gombert M E, Shulman M

出版信息

Antimicrob Agents Chemother. 1981 Oct;20(4):553-5. doi: 10.1128/AAC.20.4.553.

Abstract

The activities of cefotaxime, moxalactam, MK 0787 (N-formimidoyl thienamycin), ampicillin, oxacillin, vancomycin, and clindamycin were compared against gram-positive cocci. MK 0787 was the most active and moxalactam was the least active of these drugs, except against methicillin-resistant Staphylococcus aureus, where vancomycin was most active, and penicillin-resistant pneumococci, where cefotaxime was more active.

摘要

比较了头孢噻肟、拉氧头孢、MK 0787(N-甲脒硫霉素)、氨苄西林、苯唑西林、万古霉素和克林霉素对革兰氏阳性球菌的活性。在这些药物中,MK 0787活性最强,拉氧头孢活性最弱,但对耐甲氧西林金黄色葡萄球菌,万古霉素活性最强;对耐青霉素肺炎球菌,头孢噻肟活性更强。

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本文引用的文献

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In vitro activity of thienamycin.硫霉素的体外活性。
Antimicrob Agents Chemother. 1978 Sep;14(3):436-8. doi: 10.1128/AAC.14.3.436.
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