Tzipori S, Makin T, Smith M, Krautil F
Aust Vet J. 1982 Jan;58(1):20-3. doi: 10.1111/j.1751-0813.1982.tb00572.x.
Colostrum-deprived, colostrum-fed or suckling foals were orally inoculated with foal rotavirus and enterotoxigenic Escherichia coli derived from a calf. Neither agent given alone caused diarrhoea in foals aged 1 or 2 days, although with rotavirus, 2 of the 3 inoculated foals became depressed 3 days after inoculation and all 3 were excreting rotavirus in the faeces. Inoculation of both agents induced diarrhoea in colostrum-deprived, colostrum-fed or suckling foals aged up to 16 days. There was an apparent age-related resistance to diarrhoea which developed between 2 and 3 weeks of age. It was related to failure of rotavirus to establish apparent infection in older foals and was independent of preinoculation maternal antibody.
对未摄入初乳、摄入初乳或正在哺乳的马驹经口接种源自一头小牛的马轮状病毒和产肠毒素大肠杆菌。单独给予任何一种病原体都不会使1日龄或2日龄的马驹发生腹泻，不过接种轮状病毒后，3匹接种马驹中有2匹在接种3天后精神沉郁，且所有3匹马驹粪便中都排出了轮状病毒。对未摄入初乳、摄入初乳或正在哺乳且年龄达16日龄的马驹接种这两种病原体均诱发了腹泻。在2至3周龄之间出现了明显的与年龄相关的腹泻抵抗力。这与轮状病毒在大龄马驹中未能建立明显感染有关，且与接种前的母源抗体无关。
