Buonocore G, Pinsuti A M, Berti D, Gatti G, Rombai V
Boll Soc Ital Biol Sper. 1982 May 15;58(9):546-50.
The measure of superoxide anion (.O2-) generation was carried out in the neutrophils (PMNs) of newborns. Comparison between .O2- generation in the resting state and after stimulation with zymosan was considered. PMNs were incubated in their own plasma and in plasma from healthy adult subjects. The results demonstrate a decrease of .O2- generation (in comparison with adult PMNs) in the PMNs from newborn when they were incubated in their own plasma while the .O2- generation reached the values equal to adult's PMNs when the cells of newborns were incubated in the adult's plasma. However PMNs from some newborns demonstrated a low .O2- generation even though they were incubated in adult's plasma. The data are suggestive of a predominant, but not always exclusive, responsibility of plasma factors in the decrease .O2- generation by PMNs of full term babies.
在新生儿的中性粒细胞（PMN）中进行超氧阴离子（.O2-）生成的测量。考虑了静息状态下和经酵母聚糖刺激后的.O2-生成之间的比较。PMN在其自身血浆和健康成人受试者的血浆中孵育。结果表明，当新生儿的PMN在其自身血浆中孵育时，.O2-生成减少（与成人PMN相比），而当新生儿的细胞在成人血浆中孵育时，.O2-生成达到与成人PMN相等的值。然而，一些新生儿的PMN即使在成人血浆中孵育也表现出低.O2-生成。数据表明，血浆因子在足月婴儿PMN的.O2-生成减少中起主要但并非总是唯一的作用。
