[1型脊髓灰质炎病毒中由中和抗体诱导产生的结构多肽VP1]
[Structural polypeptide VP1 in poliovirus type 1 induced by neutralizing antibodies].
作者信息
Blondel B, Crainic R, Horodniceanu F
出版信息
C R Seances Acad Sci III. 1982 Jan 11;294(2):91-4.
PMID:6282399
Abstract
Anti-type 1 (Mahoney) poliovirus neutralizing antibodies were obtained by immunizing rabbits with structural polypeptide VP1. This polypeptide was isolated from the virion by PAGE-SDS electrophoresis and extracted from the gel by electroelution. Anti VP2 and anti VP3 sera prepared in the same was did not display any significant antipolio neutralizing activity.
摘要
通过用结构多肽VP1免疫兔子获得了抗1型（马奥尼株）脊髓灰质炎病毒中和抗体。该多肽通过SDS-聚丙烯酰胺凝胶电泳从病毒粒子中分离出来，并通过电洗脱从凝胶中提取。以同样方式制备的抗VP2和抗VP3血清未显示出任何显著的抗脊髓灰质炎中和活性。
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