Engleberg N C, Holburt E N, Barrett T J, Gary G W, Trujillo M H, Feldman R A, Hughes J M
J Infect Dis. 1982 Jun;145(6):894-8. doi: 10.1093/infdis/145.6.894.
Analysis of outpatient visits for diarrheal disease at the San Carlos Apache Reservation, Arizona, during 1977-1979 revealed a sharp increase in cases of infantile gastroenteritis of unknown etiology in October and November of each year. During the 1980 autumn diarrhea season, 19 patients and 12 control subjects were selected from among outpatients under two years of age and were interviewed and studied for bacterial and viral enteric pathogens. Eleven (58%) of 19 patients and two (17%) of 12 control subjects were positive for fecal rotavirus by enzyme-linked immunosorbent assay (P = 0.03). Ten (91%) of 11 rotavirus-positive patients were under one year of age. The most significant risk factor for illness was the presence of a household contact under the age of two years (P - 0.004). Dog ownership was also associated with rotavirus infection (P = 0.05).
对亚利桑那州圣卡洛斯阿帕奇保留地1977年至1979年期间腹泻病门诊就诊情况的分析显示，每年10月和11月病因不明的婴儿肠胃炎病例急剧增加。在1980年秋季腹泻季节，从两岁以下门诊患者中选取了19名患者和12名对照对象，对其进行访谈并研究细菌和病毒肠道病原体。通过酶联免疫吸附测定法，19名患者中有11名（58%）粪便轮状病毒呈阳性，12名对照对象中有2名（17%）呈阳性（P = 0.03）。11名轮状病毒阳性患者中有10名（91%）年龄在一岁以下。患病的最显著风险因素是家中有两岁以下的接触者（P = 0.004）。养狗也与轮状病毒感染有关（P = 0.05）。
