Brick J F, Gutmann L, McComas C F
Neurology. 1982 Jun;32(6):618-22. doi: 10.1212/wnl.32.6.618.
Maneuvers designed to manipulate ionized calcium (Ca++) were carried out in two patients with inflammatory polyradiculoneuropathy and myokymia. Increased clinical myokymia and myokymic burst amplification occurred when ionized Ca++ was lowered by plasma exchange or hyperventilation. Increasing ionized Ca++ (by intravenous infusion of CaCl2) decreased the myokymia. These findings indicate that myokymic discharges are altered by changes in serum ionized Ca++ and effects on axonal excitability.
对两名患有炎性多神经根神经病和肌纤维颤搐的患者进行了旨在调控离子钙（Ca++）的操作。当通过血浆置换或过度通气降低离子钙水平时，临床肌纤维颤搐增加且肌纤维颤搐爆发放大。增加离子钙（通过静脉输注氯化钙）可减少肌纤维颤搐。这些发现表明，血清离子钙的变化以及对轴突兴奋性的影响会改变肌纤维颤搐放电。
