Hussa R O
Obstet Gynecol. 1982 Jul;60(1):1-12.
Sensitive and quantitative radioimmunoassays of serum human chorionic gonadotropin (hCG) levels have expanded the utility of hCG measurements from a simple pregnancy test into a powerful tool applicable in an increasing number of clinical disorders. Proper management of gestational trophoblastic disease depends on reliable and sensitive hCG determinations. Information on the in vivo doubling time of hCG in early pregnancy can be used in more effective diagnosis of early pregnancy disorders such as ectopic pregnancy and spontaneous abortion. Serum hCG is an effective tumor marker in the staging and management of testicular cancer and potentially of nontrophoblastic cancers. Measurement of glycoprotein hormone alpha-subunit levels has clinical application in gestational trophoblastic disease, abnormal pregnancy, and some forms of nontrophoblastic malignancy.
血清人绒毛膜促性腺激素（hCG）水平的灵敏且定量的放射免疫测定法，已将hCG测量的用途从简单的妊娠试验扩展为一种强大的工具，可应用于越来越多的临床疾病。妊娠滋养细胞疾病的妥善管理依赖于可靠且灵敏的hCG测定。妊娠早期hCG在体内的倍增时间信息，可用于更有效地诊断早期妊娠疾病，如异位妊娠和自然流产。血清hCG是睾丸癌以及可能的非滋养细胞癌分期和管理中的一种有效肿瘤标志物。糖蛋白激素α亚基水平的测定在妊娠滋养细胞疾病、异常妊娠和某些形式的非滋养细胞恶性肿瘤中具有临床应用价值。
