Goh K T, Doraisingham S, Yin-Murphy M
Southeast Asian J Trop Med Public Health. 1981 Dec;12(4):473-86.
The clinical, epidemiological and virological findings of the 1980 epidemic of acute conjunctivitis were described. Enterovirus 70 was isolated from 7 (35%) of 20 eye swabs submitted for virus isolation, and the paired sera of eight patients showed a four-fold or greater rise in neutralising antibody titre to Enterovirus 70. The disease mainly affected children and young adults of all ethnic groups. Most of the cases contracted the infection at home. The mean secondary attack rate was 72.6% and the mean incubation period, four days. The clinical features were similar to the 1970 and 1975 epidemics caused by Coxsackievirus A24. Subconjunctival haemorrhage was observed in 10% of the cases. Most of the cases recovered spontaneously within a week. Transmission of infection within the home was either indirect, probably through fomites contaminated with eye or respiratory discharges of cases, or direct, through intimate person-to-person contact. During outbreaks, health education on simple personal hygiene should be highlighted.
描述了1980年急性结膜炎流行的临床、流行病学和病毒学发现。从提交病毒分离的20份眼拭子中的7份（35%）分离出肠道病毒70，8例患者的双份血清显示对肠道病毒70的中和抗体滴度有四倍或更高的升高。该病主要影响所有种族的儿童和年轻人。大多数病例是在家中感染的。平均二代发病率为72.6%，平均潜伏期为4天。临床特征与1970年和1975年由柯萨奇病毒A24引起的流行相似。10%的病例观察到结膜下出血。大多数病例在一周内自发康复。家庭内感染传播要么是间接的，可能通过被病例的眼部分泌物或呼吸道分泌物污染的污染物，要么是直接的，通过密切的人际接触。在疫情爆发期间，应强调关于简单个人卫生的健康教育。
